Enanta is seeking an enthusiastic and highly motivated Scientist who will be responsible for LC/MS/MS bioanalytical method development/validation, biological sample analysis, and in vitro/ex vivo drug metabolism studies. The successful candidate must have in depth knowledge of regulatory guidance for bioanalysis and GLP compliance, separation science, analytical instrumentation (e.g., API 6500 & 4500 LC/MS/MS, etc.) and their application to bioanalysis. Excellent written and oral communication skills, as well as strong organizational skills are essential. Flexibility and adaptability are also necessary.
Design and oversee GLP-regulated bioanalytical method development, validation, and sample analysis
Manage a bioanalytical lab and keep the instruments running properly.
Conduct enzymatic assays and in vitro/ex vivo drug metabolism studies, including liver microsome stability testing in different species, cytochrome P450 inhibition, hepatocyte metabolism, and metabolite identification, etc.
Address and resolve scientific issues arising in drug discovery/development programs.
Interact with multidisciplinary teams (including chemists, toxicologists, and clinical managers) to meet project goals and timelines.
Communicate unambiguous critical and significant project information to various bodies including project teams and Enanta leadership as required.
Collaboration & Teamwork: Relates to employees and management in a cooperative manner that helps others to achieve their best.
Productivity/Organizing/Planning: Meets deadlines, demonstrates effective use of time, and handles multiple assignments simultaneously.
Communication Skills: The ability to convey both written and verbal information effectively and efficiently.
Willingness to Acknowledge Areas for Growth: Understands need for growth and is receptive to constructive feedback.
Detail-Oriented: Follows precise procedures and demonstrates thoroughness in performing job tasks and assignments.
Education, Prior Work Experience, and Specialized Skills and Knowledge
Ph.D. in Bioanalytical Chemistry or relevant field.
A minimum of three years of experience with bioanalytical method development and validation.
In depth understanding and working knowledge of regulatory guidance for bioanalysis and GLP compliance.
How to Apply
Please complete the online application (click on "apply now" link above) and include the following attachments:
Research Summary (if applicable)
Enanta Pharmaceuticals is an equal opportunity employer (EOE) with a commitment to diversity. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to race, color, national origin, age, religious creed, gender, gender identity, sexual orientation, physical or mental disability, protected veteran status, or any other class protected by law.
Internal Number: PK411
About ENANTA Pharmaceuticals, Inc.
Enanta Pharmaceuticals Inc., is a research and development-focused biotechnology company dedicated to creating small molecule drugs for viral infections and liver diseases.
Two protease inhibitors, glecaprevir and paritaprevir, discovered and developed through Enanta’s collaboration with AbbVie, have now been approved in jurisdictions around the world as part of AbbVie’s direct-acting antiviral (DAA) regimens for the treatment of hepatitis C virus (HCV) infection, including the U.S.-marketed regimens MAVYRET™ (glecaprevir/pibrentasvir) and VIEKIRA PAK® (paritaprevir/ritonavir/ombitasvir/dasabuvir).
Royalties from the AbbVie collaboration are helping to fund Enanta’s research and development efforts, which are currently focused on the following disease targets: non-alcoholic steatohepatitis (NASH), primary biliary cholangitis (PBC), respiratory syncytial virus (RSV) and hepatitis B virus (HBV).